The result is a better and enhanced erectile function.
Tadalafil (trade name Cialis ®) has no effect in the absence of sexual stimulation and must not be used by anyone who does not suffer from erectile dysfunction.
Tadalafil is the third oral product, in terms of time, approved for this circumstance.
This medicine differs from previous products as it stays longer in the body, maintaining its effective effectiveness even up to 36 hours, plus minor secondary effects.
The chemical formula of the Tadalafil molecule is 6R-trans) -6- (1,3-benzodioxol-5-yl) – 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1 ‘, 2 ‘: 1,6] pyrido [3,4-b] indole-1,4-dione C22H19N3O4.
Tadalafil therefore acts against erectile dysfunction by inhibiting the enzyme phosphodiesterase type 5 (PDE-5), allowing the guanosine-monophosphate-cyclic molecule to fulfill the erection effect of the penis.
It works by increasing the effects of one of the chemicals that the human body normally produces during sexual arousal and therefore allows an increase in blood flow.
This results in an easier and faster erection, as well as more prolonged over time.
The action is that in practice to stretch the muscles in the penis and the blood vessels, allowing the blood flow to flow into the penis.
Unlike Sildenafil, the active substance of Tadalafil has a longer half-life (approximately 17 hours), allowing a longer effect, estimated at around 36 hours.
In particular, in the case of a sexual stimulus, the human body secretes a substance called guanosine-monophosphate-cyclic (cGMP): this is what causes the erection of the penis in man.
It is the guanosine-monophosphate-cyclic that generates the enlargement of the penis with the flow of blood inside.
When sexual excitement is present in the brain, a real “chain of events” begins in the human body.
This chain of events is on the one hand made up of psychological factors and on the other side of physical factors, all of this culminates with the production of cGMP in high levels within the tissues of the penis.
When cGMP reaches certain levels, the enlargement and hardening of the penis is generated, called in the particular “erection”.
The greater the amount of cGMP, the longer the duration and the extent of the erection.
Furthermore, until a high level of cGMP exists, the male organ lasts in a state of valid erection.
The lapel of the medal, that is, what damages the cGMP is the enzyme PDE-5 (phosphodiesterase 5).
The production of this enzyme (PDE-5) occurs naturally in the body and its effect is to counteract and cancel the cGMP.
So if there are high levels of PDE-5 in the body at any given time, the cGMP enzyme is not able to carry out its targeted action, ie the erection is not achieved or is reached in a modest manner for cialis generic cheap.
Furthermore, there is an absolutely negligible and passing erection.
It is important to remember that in the brain there is excitement and stimulation but it is not possible to harden the penis or the hardening is limited to a short time.
It is a situation of great psychic distress.
Tadalafil aims to block the PDE-5 enzyme.
With the assumption the PDE-5 is effectively opposed and instead allows the cGMP to carry out its action in complete tranquility.
The result of these chemical actions in the male body leads to the end result of a robust, effective erection lasting over time, so as to allow a sexual relationship without thought.
Tadalafil, therefore, maintains a high level of cGMP produced initially with sexual arousal and as long as this stimulation continues producing and inducing erection, the penis remains in its state of swelling and turgidity and also to a greater extent.
Men in difficulty and who can use them will “bless” the yellow pill.
Tadalafil does not generate a direct erection but generates it in a natural way only when there is sexual excitement.
This means that taking the drug does not have the unnatural effect of a thick and hard penis, but only in the presence of a sexual stimulus.
This anti-impotence drug causes the consequence at the level of the male sexual organ of an immediate erection.
In the absence of stimulation, it is good to remember it, it is not produced and therefore there is no erection.
With Tadalafil then you do not have an erection if you do not want it and this is correct.
Helps achieve erection faster with energy and decisively and by the total duration in which cGMP is present, ie erection will occur throughout the excitement phase.
It is rapidly absorbed into the bloodstream, after only thirty minutes it is already in circulation and reaches its maximum concentration within two hours.
Tadalafil will remain in the body for two days, maintaining a level of effectiveness for approximately thirty-six hours.
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